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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edb5c288cd823ab53abe5728c9c9c7214f0a188497805b8e99b8aa0e23b76af3' 
  AND token = 'cs5PhFcGkYTOFU+5LtJtmbelAf1FsM4DZwy5Mr9QAK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}