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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4725941463f34702c8538b9648ea4381b3b2cbb1a1ec263d0de26bd82de2b3d7' 
  AND token = 'Jn3VfC7F8+49zWgvevoUb3sB6v3UUxLXDeVwkc/0nXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}