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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5580dc9a7dc58246e308e12dc08e2f58f63676909ee903a5352364c7f2c11431' 
  AND token = 'r8lBXS1e5iRYGFm0wLBgUsUgAxuoTCTthEl9m9AVZZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}