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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39f5795b62af2bd7f5dd02e483b65e3dd2b52d27ac9686fb6bc7c476632da472' 
  AND token = 'TU4hhutmJxC34uLu0gKG9OQDqW1NPdkFRMIQqDxXSQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}