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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e351ff94a7e669692f040631f659acb83d6f9e99ca20b4dc7391da5f94c258f' 
  AND token = 'vmTELLsRIVa3sO3PJ2bHHvYfIxbUpukrArfSjqEgpyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}