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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a77089f5e368e2c2cb29ded73e82c3735428636b78e0ca0bdb1c87ba16ba6b54' 
  AND token = 'SHxnjX5jWrC4dgW5x5gr0hKCh/aSUBlKIMFHRtjD6nY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}