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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d4fa6e20d310c2789f0effd81dba4c3450c6d854db6d4bd9b8c23547f74243' 
  AND token = 'xPHivr2U/afDnTorhPl/8yuIr6pyyvYv4Av0aFhrhLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}