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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd50c779d50ceacba61e22e3816e639535b234e72a890f8f4fdd51616898a3fb' 
  AND token = 'dXNy5OzA/G0z5d5VmvnzB7mY860LvQIMBN0mL7s2zUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}