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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b40097bbca0be5729400de44001fc6e864e39723a72749f93cd41d84b9e44ee5' 
  AND token = 'cO9qycFvL5i9WDpwCHe/c9Egx3PbDRFpYtAfe4Gj9Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}