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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '725b4bf5b21f68cf20f3a96499966589fc21902b28f040545508a058b8500e74' 
  AND token = 'QGVaVmI3IifTkv08JNNg5f6sg6wm//qknI7EV3OQwqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}