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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57d65d00598bc023aa4d73cd2527509807c9ee5b728ff1482faec1856e27019' 
  AND token = 'nqOHENcCrYYyVBSqSUtk18CoYgXmyBX8W3UjnjZo2f8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}