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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c55af0703fb131f7dcfc581dd5bf643963e562e7c6a42998bcdebe9cff7e071' 
  AND token = 'fzI0ZNS2po8Rys0nRzhiv8H3+BsvHVrEvax6bJm5Cqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}