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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4def54ae85c3dd2b12cf776e9ae6a394fd811735b8226cb79f5abae2a575028e' 
  AND token = 'AkHKYUD2arZM5SXsEZSCZupNCv1CMQTFUJjGlk1cwP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}