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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa10fff4fd81022ecf58e56aea342bd2de07aebde1a51227d9605802be80e5c9' 
  AND token = 'NkYyIxHuAS4RN54cVG+wMffU8egBdnTgVkDg223V/Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}