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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f7f7378d5e99d33968fc024bfdc33763e9b4b0d9479c703086ebc5974521143' 
  AND token = '0VbLpBIifeXufXf9P9FGDY33WwGwyjXbB07Q0FKK3zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}