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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43004a18a457b35894df2d614e51d6a21aedcd57e22923b30b749431ab55b4d4' 
  AND token = '3/fRdP1nzCRrLBJm4wGO6w20HSl48Oc/v2P6tTJ7i1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}