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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '775ece73d59ec58aebd29a83a923d58a960af4ac8d252fe24b7961ffd18169b1' 
  AND token = 'O+ZJtOyxBCiPKeVhV4t+9UUOj5aXizUbSLra86eeQU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}