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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f654c4d63ebabe0715f6d67c1b7b69969dd5102f61e8c9099db6fd1c5f9a1481' 
  AND token = '2vd25LmrByXapXa53TbOc9MS9FhsNitfE8TC5ssjT/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}