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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b395e0646ebe2b8f2a242739d46613016503d06fed8fbf428caca23c746148be' 
  AND token = 'sFrybCDs/yktxFuJQldA3Cb9zPi1G9E9ZlLM1pnJurQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}