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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6df9874b053033d1eed26dfa5f0d543933896b80d6c7b1aa8144b81d701f3910' 
  AND token = '7E3CUkV3MMO8Hichmdv6nNUEr+sYtTNzHy9EtiudWIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}