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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ff2e11a2273e5c9f0c2f4c24b0757067990ab2e4af282c96e208b55a47d9ce' 
  AND token = 'vXhYHmGdZ5KcxW3vMoH5HwPyreB/hp0BZSvEiHmBVX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}