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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c181a9a890784cd336664b15bffc9156760900dd088780d18ee45f926c57151' 
  AND token = 'q0OC1thj1ogRVI//q1fkUj/NYeQMs2GUAqaTSiEuxLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}