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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644508b2e5e079c5f6a8338777dc25ae4e884b3a53df77b3dd68bdc2d62e76c8' 
  AND token = '1fjZ7HZk8YASG+vKzFLzdE+IGi9I4bkk4GqVT7GmoR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}