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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8404e3bc0dbb49d6a64a8e4c1c126157c718d2fddab31e3a09b8b710913b3ebc' 
  AND token = 'CiHwTROOD2uV7MoVxBH5ELhXqQQ+txnu2Xt3vZNBC4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}