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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b49dc4b1369c408306b1cba1c4c4149f9c08b976a01c214ddedac2de6ec2078' 
  AND token = 'AQGRpUpCCUWpV4dC/a4F84Ii1UFb0O8jMJAZ2RnV0ME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}