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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eac52a65bd9c4021ceeabac0c4c2f977aa57611ff5babdbd5ed66ac80e42e13b' 
  AND token = 'qipVjTS5L2yBlZSbW7m5odhJMUIuCofaps7WcgetnMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}