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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c4bd66f5fe20f5817562be88c1e4e78d97a543b0d56da96f0bc4673906e0c29' 
  AND token = 'RR3yQEDUEnTDzL24nX3tUSoX14X5wVIoiftqjLkdNjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}