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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17f5246f3c829664751657c36e8288f366ff5cb373e37116d3388db251ca29a2' 
  AND token = 'tuCQHDENqsxkCfBLmzOzp6aC9iaSN1p+RpEitxytPng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}