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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '419e5d5b66a1cd033987dcec3d3c016bfbd9be1f4f668055e50a8e7431a39ec2' 
  AND token = 'Ib2wXaNmH3X+yvW5KB6hPipD25uTlEfjjwEHgUa3yg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}