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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63fc443a99c1b722fef0b65366c06c3cb2cec1fa7c16155bd65b770275ca743' 
  AND token = '1wlDgwLP7emu2i48lLwT4vrGzl2zlodRBpAjCZ/71zI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}