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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46d25eef98740e2dc2fd365e85eaf73ffdeed6a36faa07140e2f84db606ce81' 
  AND token = 'ciGWkAiw4uCcu9xpPwb5+XenbfBKXQA5h53bR2NqB/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00088

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}