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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acca8e7f27a3e94363824c8563ad0e192f84034b727f135de70e36a6364a9ed1' 
  AND token = '7ph2vTQeah1i17mU6NeEAb5XPk05OVAHnl5lMSv6sxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}