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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad2b614ad845c1fa405712a4ef5b628db040fd1ed298c985045d70c86bdc2d7' 
  AND token = '3UaAp6uvwitbuCWpwE+SsmrHwpHILsZDTlWvGwSzJYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}