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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd88dd8f078836d3df986a1acf724f12a17bcce71e9e9f61b03f22d31ea292172' 
  AND token = '8mt798VCFAse4O5I2czh8+7UxDdNW6vYUvLsS93fkFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}