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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5144f811154c72fa35402bb335ed20811b5d67251ec37e58139201cf71eaef22' 
  AND token = '4IxIVPa+1ix+rf2AFNxk+Z7jBy9tAv/xZPiFA/Qc0Ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}