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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4c1e72e67e98d5d65baf2f00f7f354604842829ab8fff3789371b0f06e0a206' 
  AND token = 'EW0+VhDeC9kF+4lEOkpvszqyv2ephJyAMexHy/6BT6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}