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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55d4aef3d5887859bfffcf38e2151df38437a1e3505801c98a7b14ca6d6ca151' 
  AND token = 'J40IpG2Bx9ID+zw4lfH9vjq1gteN7vPZICBpD5sA9PI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}