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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c2f11bc59c4570070cdb5a5582ee969e07521d6e3d98c588ac36777f526b78f' 
  AND token = 'qYb3w5M2c8KI2rYKMPCLqKHxDubPjLD3C/5GidI+Hgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}