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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9195a28b190bf5c862c5b0e189b7175452a60820bb94728c98065ca59d6758' 
  AND token = 'GUzDvGF2Oalj8am5MWq5DPvDn0hl2WNYbaisNV4+At0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}