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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '435d9fd6d7d117ef480febaa9e2090c98fa4581de5b2a482d6dedd49eab785de' 
  AND token = 'FnzUi4gMt0Ny6ZAni8CZK68RUazQA+hEMo2cmHdcBo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}