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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b163a2071b820bd44cbf7143d8861e8fb554842ecdc4bfc0925fade8429b825b' 
  AND token = 'NndJMS5dfBNsYukUM1iuiiE5oyV2fD5Sf2Riqbb5mOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}