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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5480b3b914c293356c930aa4d26a6e38a8ac4e3fc1563fed8f918d1cf10e9804' 
  AND token = 't4ZAE90P2qPiH29RllcrQ1MqjJGqM3PueL3X6RIXgZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}