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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5db58d358e1fc4c8ae28b91c5827a90b99ab22791fbff874365ddeb651b56880' 
  AND token = 'OTWVJRuZ/G+bhaEVK7CnXZ22PfFZuke72j+4rMAA/nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}