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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5344f33e4b08c3a2f7b094504d36c48ea9a1839b8ff14232460b7db494468c8' 
  AND token = '/vXRSX6uzkKJF/cgw/r88OuFnuCgR24KVZ+FWHNA38Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}