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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abd6cab554e8f495bd01701086d55f79caf9fb6e27932d9c657d2c406e143d50' 
  AND token = 'kMSe3qSICfTsx0IRoJOJLZBzRXQOcpDiJDcQ0pHHxvo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}