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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b56677935ca570afdb21daeb66c64a5a76bf0381950f2f36e80a7ac55d76a647' 
  AND token = '9dHOxTQ8XHfRqL/8NrqMc05bBK7zM9E4MWXWzatIdzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}