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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185b42b47e49ac607316bf6b11d10230a35602168bb0a4296402433200f571e2' 
  AND token = 'gFmd+MK1MWyKtd2lgUs3mRPTwaDxb9c3OlTe8oSGsrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}