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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a1aa898ecb48421a6ad3f2ed205a722ee14ee3817d132cf4866d93a11da1dd' 
  AND token = 'QSzyEzzLtqryM37B/E5gjEL1vfRL8gPRpIBGpoaCLyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}