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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c26301414be5ee17b501bddba7aee276c8ec27e37c460e7ef1428a8a15fe849' 
  AND token = '5V1FM2LzZj5sLWpul05BZHXx0tuAqs7oA/8s2HUfhyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}