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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291e41fe0c9d53d0567ee3d19e7f59bf22748aae669bcc5aec2659cfbb91b5c3' 
  AND token = '0ACX+vKU6/bQUX0yPV1TFo2dLdNn2zT2LSIzuP+bgaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}